Concomitant Use

Compatible with Restasis*

When adding an adjunct treatment for the moderate to severe dry eye cases, SYSTANE® combined with Restasis* is more effective compared to Refresh Tears* + Restasis*.

In a multicenter, double-masked, randomized, controlled study of aqueous deficient patients with corneal staining, SYSTANE® alone provided significant reduction in corneal staining from baseline at 6 months (p=0.0004).1

The same study also showed a clear statistical difference favoring the SYSTANE® + Restasis* dry eye treatment combination compared to Refresh Tears* + Restasis* in the reduction of corneal staining from baseline at 6 months.1

Dry Eye Symptoms Composite

§Symptoms measured over the last 3 days of each treatment period.

  • SYSTANE® alone was shown to be more effective than the Refresh Tears*/Restasis* combination in reducing the four symptoms commonly associated with dry eye and ocular discomfort: burning, dryness, grittiness, and foreign body sensation (p = 0.0480)1
  • Overall, Restasis* used with SYSTANE® was significantly superior in reducing the 4 symptoms vs the Refresh Tears/Restasis* combination (p = 0.0191)1

Use SYSTANE® when adding an adjunct for your most severe cases.

  • In hard-to-treat cases, continue using SYSTANE® Lubricant Eye Drops and add Restasis* as an adjunct therapy to increase tear flow. 1,2
  • SYSTANE® is fully compatible with Restasis* The combination of SYSTANE® + Restasis* is more effective.1

  1. Sall KN, Cohen SM, Christensen, MT, Stein JM. An Evaluation of the Efficacy of a Cyclosporine-Based Dry Eye Therapy when used with Marketed Artificial Tears as Supportive Therapy in Dry Eye. Eye & Contact Lens. 2006;32(1):21-26.
  2. Restasis* prescribing information.

* Trademarks are the properties of their respective owners.

SYSTANE®

SYSTANE®

SYSTANE® Lubricant Eye Drops helps protect eyes from dry eye and keeps them lubricated throughout the day.

Learn More
SYSTANE®

SYSTANE®

SYSTANE® Lubricant Eye Drops helps protect eyes from dry eye and keeps them lubricated throughout the day.

Learn More